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Influence of green tea on surface charge density and phospholipids composition of erythrocytes membrane in ethanol intoxicated rats.

Szachowicz-Petelska B, Dobrzyńska I, Skrzydlewska E, Figaszewski Z

Institute of Chemistry, University of Białystok, Al. Piłsudskiego 11/4, 15443, Białystok, Poland.

Ethanol is oxidized to acetaldehyde and then to acetic acid and these processes are accompanied by free radical generation. This paper reports the effect of green tea on electric charge and phospholipids composition of erythrocytes membrane from rats intoxicated with ethanol. Electrophoresis technique and HPLC have been applied to above-mentioned studies. Ethanol administration caused increase in erythrocyte membrane surface charge density and phospholipid composition. Ingestion of green tea with ethanol partially prevented changes in structure and function of membrane caused by chronic ethanol intoxication.

Published 3 May 2005 in Cell Biol Toxicol, 21(1): 61-70.
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